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These include the usual suspects, like semaglutide and tirzepatide, but also retatrutide, the GLP-1 drug still being tested in clinical trials

In Vitro Research

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In contrast, the 2,3-diamino substitution in the 1MQ scaffold (2,3-diamino-1MQ) displayed high passive permeability (Table 1), but moderate bi-directional active transport with moderate efflux ratio (Table 2)