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CONCLUSIONS HLHS, although less common than other CHD heart defects, remains a compelling field of study due to its significant mortality and morbidity rates, necessitating further exploration of effective treatment modalities

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Following Coley and Ehrlich, sequential efforts for the development of many cancer therapeutics took place in the 1900s, including DNA analogs, antimetabolites, cytotoxic molecules, protein tyrosine kinase inhibitors, and finally, monoclonal antibodies [3]