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rxlist.com (Enlon ®) Keywords Organophosphate Cholinesterase Inhibitors Echothiophate Trade Name: Phospholine Iodide ® Drug Class: Anticholinesterase ( Organophosphate ) Mechanism of Action: for topical use to enhance the effect of endogenously liberated acetylcholine in the iris, ciliary muscle, and other parasympathetically innervated structures of the eye Irreversible long-acting cholinesterase inhibitor It causes miosis, increases the outflow of aqueous humor, causes a fall in intraocular pressure, and potentiation of accommodation Indications: Historically used for treatment of glaucoma but currently very rarely used, and frequently regarded as “obsolete” for the routine treatment of glaucoma (Figure 1)
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123 It is generally believed that the lower the conformational stability energy of the ligand and the receptor, the greater the possibility of interaction, based on the choice of the degree value of the top core target in the corresponding active ingredient for docking as shown in Fig
